Mashiinka ka hortagga kansarka ee Paclitaxel.Maxaad taqaanaa?

Paclitaxel waa dawada ka hortagga kansarka oo loo isticmaalo in lagu daweeyo noocyo badan oo kansar ah, waxaana markii hore laga soo saaray jilif geedka Yew Pacific (Taxus pacifica) ka dibna waxaa soo saaray hababka synthetic.PaclitaxelWaxay ka tirsan tahay fasalka dawooyinka loo yaqaan stabilizers microtubule.

Habka ka hortagga kansarka eepaclitaxelWaxay ku lug leedahay dhinacyo badan, oo ay ugu badan yihiin kuwan soo socda:

1. Kordhinta xasilloonida microtubule:Paclitaxel waxay ka hortagtaa xasilloonida firfircoonida caadiga ah ee microtubules iyadoo ku xidhan tubulin, taas oo qayb ka ah cytoskeleton. sifo muhiim ah oo kansarka ah, sidaas darteed xakameynaya kala qaybinta unugyada iyadoo la dejinayo microtubules waa habka muhiimka ah ee ka hortagga kansarka ee paclitaxel.

2.Cell cycle arrest:Paclitaxel waxa kale oo ay sababi kartaa xidhidh wareegga unuggu,taas oo keenta in unugyada kansarku ay istaagaan marxalad wareeg ah oo unug gaar ah,sida caadiga ah mitosis

3.Waxay kor u qaadaa apoptosis:Paclitaxel waxa laga yaabaa in ay hor istaagto korriinka kansarka isaga oo kicisa unugyada kansarka ee dhaawacan ama aan caadiga ahayn si ay u galaan apoptosis(dhimashada unugyada qorshaysan)

4.Anti-angiogenesis:PaclitaxelWaxa kale oo ay xannibi kartaa samaynta xididdada dhiigga cusub ee agagaarka unugyada kansarka, kuwaas oo lagama maarmaan u ah koritaanka burada iyo faafitaanka. By ka hortagga samaynta xididdada dhiigga cusub, waxay hoos u dhigi kartaa sahayda dhiigga ee burada, si ay u xaddido koritaanka burada.

Guud ahaan, paclitaxel waa daawo faragelisa koritaanka iyo kala qaybinta unugyada kansarka, oo ku hawlan unugyada kansarka iyada oo loo marayo habab kala duwan, sidaas darteed si ballaaran ayaa loo isticmaalaa noocyo badan oo daaweynta kansarka ah.

Fiiro gaar ah: Faa'iidooyinka iyo codsiyada suurtagalka ah ee lagu soo bandhigay maqaalkan waxay ka soo jeedaan suugaanta la daabacay.

Yunnan Hande Biotechnology Co.,Ltd.wuxuu diiradda saarayaa wax soo saarkapaclitaxelmuddo 26 sano ah, waana soo-saare madax-bannaan oo ka mid ah dawada paclitaxel API ee laga soo saaray warshadda oo ay ansixisay FDA Maraykanka, Yurub EDQM, Australia TGA, Shiinaha CFDA, Hindiya, Japan iyo hay'adaha kale ee sharci ee qaranka. Yunnan Hande paclitaxel, sahayda dhibicda Iibka tooska ah ee warshadda, soo dhawoow si aad wax u weydiiso,18187887160(WhatsApp isku mid ah)