Paclitaxel (Paclitaxel) waa daawo leh qaab dhismeed adag oo laga soo saaro dhirta dabiiciga ah, iyo sifooyinkeeda gaarka ah ee ka hortagga kansarka ayaa ka dhigaya inay leedahay codsiyo ballaaran oo dhanka caafimaadka ah.Si kastaba ha ahaatee, ay sabab u tahay naadirka iyo adkaanta soo saarista, wax soo saarka eepaclitaxelayaa caqabad noqotay.Sanadihii la soo dhaafay, iyada oo loo marayo dadaalka farmashiistaha Faransiiska, walaxda loo yaqaan 10-DAB ayaa si guul leh looga go'doomiyay caleemaha guduudan ee Britishka ah, kuwaas oo qaab-dhismeedkoodu uu la mid yahay paclitaxel iyo nuxurka ka sarreeya, taas oo bixisa suurtogalnimada in lagu xalliyo dhibaatadan.
Doorka paclitaxel
Daawada ka hortagga kansarka, habka ugu weyn ee paclitaxel ee ficilku waa inuu sameeyo saameyn liddi ku ah burooyinka iyadoo la xakameynayo qaybta unugyada burooyinka.Waa microtubule inhibitor, kaas oo kor u qaadi kara polymerization ee tubulin iyo in la xakameeyo depolymerization, sidaas oo ay u joojiyaan mitosis ee unugyada burooyinka.Intaa waxaa dheer, paclitaxel waxay sidoo kale keeni kartaa apoptosis unugyada burooyinka iyadoo la kicinayo habka difaaca jirka.
2. Goobaha codsiga eepaclitaxel
1. Daawaynta burada: Paclitaxel waa tan ugu badan ee loo isticmaalo dhanka daawaynta burooyinka, gaar ahaan kuwa loo isticmaalo burooyinka halista ah sida kansarka naasaha, kansarka ugxansidaha iyo kansarka sambabada.Waxa loo isticmaali karaa kaligiis ama lagu daro dawooyinka kale ee ka hortagga kansarka si loo hagaajiyo waxtarka daaweynta.
2, qaybaha kale ee caafimaadka: Marka lagu daro daaweynta burooyinka,paclitaxelWaxa kale oo loo isticmaalaa qaybaha kale ee caafimaadka.Tusaale ahaan, waxaa loo isticmaali karaa in lagu sameeyo buuxinta ilkaha ama lafaha, sidoo kale waxaa loo isticmaali karaa in lagu daweeyo cudurrada difaaca jirka qaarkood iyo cudurrada neerfaha.
Fiiro gaar ah: Faa'iidooyinka iyo codsiyada suurtagalka ah ee lagu soo bandhigay maqaalkan waxay ka soo jeedaan suugaanta la daabacay.
Yunnan Hande Biotechnology Co., Ltd. ayaa diiradda saarey wax soo saarka paclitaxel muddo 26 sano ah, waana soo saaraha madax-bannaan ee dhirta laga soo saaray daawada kansarka ka hortagga paclitaxel API oo ay ansixisay FDA United States, European EDQM, Australia TGA, China CFDA , Hindiya, Japan iyo hay'adaha kale ee sharci ee qaranka.Yunnan Hande paclitaxel, sahayda booska, iibka tooska ah ee warshadda, ku soo dhawoow inaad waydiiso, 18187887160 (WhatsApp isla lambarka)
Waqtiga boostada: Oct-08-2023