Baro saamaynta daweynta paclitaxel ee noocyada kala duwan ee kansarka

Paclitaxel waa iskudhis dabiici ah oo laga soo saaro geedka yew, kaas oo leh hawlo muhiim ah oo ka hortagga burooyinka. si qoto dheer u baadh saamaynta daawayntapaclitaxelnoocyada kala duwan ee kansarka.

Qaab dhismeedka iyo sifooyinka paclitaxel

Paclitaxel waa isku-dhafan tetracyclic diterpenoid adag oo leh qaab-dhismeed saddex-geesood ah oo gaar ah, kaas oo siinaya saldhigga hawlaheeda ka hortagga burooyinka.

Habka ka hortagga kansarka eepaclitaxel

Habka anti-kansarka ee paclitaxel ayaa inta badan la xidhiidha xannibaadda depolymerization tubulin iyo saamaynta ay ku leedahay qaybinta unugyada iyo faafinta. Dhimashada unugga

Saamaynta daaweynta paclitaxel ee noocyada kala duwan ee kansarka

1. Kansarka naasaha: Saamaynta daweynta paclitaxel ee kansarka naasaha ayaa si weyn loo aqoonsaday. Daraasad lagu sameeyay 45 bukaan oo kansarka naasaha ah, paclitaxel oo lagu daray kiimoterabiga ayaa keentay in burooyinka ay yaraato 41% bukaannada iyo celceliska badbaadada in ka badan 20 bilood.

2. Kansarka sambabada unug yar: Kansarka sambabada unugyada aan yarayn, paclitaxel oo ay weheliso dawooyinka chemotherapy-ku salaysan ee platinum ayaa si weyn u wanaajin kara badbaadada bukaanka. daaweynta kiimoteradu waxay keentay badbaado dhexdhexaad ah oo ah 12 bilood.

3. Kansarka ugxan-sidaha: Daawaynta 70 bukaan oo kansarka ugxan-sidaha ah, paclitaxel oo ay weheliso daawooyinka kiimikaad ee platinum-ku-salaysan ayaa hoos u dhigay burooyinka 76% bukaannada, iyo heerka badbaadada labada sano ayaa gaadhay 38%.

4. Kansarka hunguriga: Daawaynta 40 bukaan oo qaba kansarka hunguriga, paclitaxel oo ay weheliso shucaaca shucaaca ayaa hoos u dhigtay burooyinka 85% bukaanada, heerka badbaadada halka sano ah ayaa gaadhay 70%.

5. Kansarka caloosha: Daaweynta kansarka caloosha, paclitaxel oo lagu daray fluorouracil waxay si weyn u wanaajin kartaa badbaadada bukaanka. Daraasad lagu sameeyay 50 bukaan oo qaba kansarka caloosha,paclitaxelMarka lagu daro kiimoterabigu waxay keentay badbaado dhexdhexaad ah oo ah 15 bilood.

6. Kansarka mindhicirka: Daawaynta 30 bukaan oo kansarka mindhicirka ah, paclitaxel oo ay weheliso oxaliplatin ayaa hoos u dhigtay burooyinka 80% bukaannada, iyo heerka badbaadada labada sano ayaa gaadhay 40%.

7. Kansarka beerka: Inkasta oo saamaynta paclitaxel monotherapy ee kansarka beerka ay xadidan tahay, isku darka daawooyinka kale ee kiimoterabiga sida cisplatin iyo 5-fluorouracil waxay si weyn u wanaajin karaan badbaadada bukaanka. Daraasad lagu sameeyay 40 bukaan oo qaba kansarka beerka ayaa muujisay in paclitaxel la isku daray. daawaynta kiimoteradu waxay keentay badbaado dhexdhexaad ah oo ah 9 bilood.

8. Kansarka kelyaha: Daawaynta kansarka kelyaha, paclitaxel oo lagu daray dawooyinka immunomodulatory sida interferon-alpha ayaa si weyn u wanaajin kara badbaadada bukaanka 24 bilood.

9.Leukemia:daawaynta acute myeloid leukemia,paclitaxel marka lagu daro daawooyinka kiimikaad sida cytarabine waxa ay bukaanada ka dhigi karaan in ay gaadhaan xadiga cafiska dhamaystiran 80% bukaannada.

10,lymphoma:Daawaynta lymphoma non-Hodgkin,paclitaxel oo ay weheliso dawooyinka kiimoterabiga sida cyclophosphamide waxay awood u siin kartaa bukaanada inay gaaraan heerar jawaab celin oo dhammaystiran. jawaab celin buuxda 85% bukaanada.

Gabagabo

Marka la soo koobo, paclitaxel ayaa muujisay waxtarka daaweynta noocyada kala duwan ee kansarka. Si kastaba ha ahaatee, waxaa muhiim ah in la ogaado in waxtarka daawadu ay kala duwan tahay nooc kasta oo kansar ah oo inta badan loo baahan yahay in lagu daro daawooyinka kale. Intaa waxaa dheer, sababtoo ah kakanaanta iyo kala duwanaanshaha shakhsi ahaaneed ee kansarka, qorshooyinka daawaynta waa in loo shakhsiyeeyaa bukaan kasta.

Fiiro gaar ah: Faa'iidooyinka iyo codsiyada suurtagalka ah ee lagu soo bandhigay maqaalkan waxay ka soo jeedaan suugaanta la daabacay.