10-DAB Semi-Synthetic Paclitaxel: Horumarka Meesha Daroogooyinka

Paclitaxel waa daawo lagama maarmaan ah oo si weyn loogu isticmaalo daaweynta kansarka, laakiin ilo dabiici ah ayaa xaddidan.Si loo daboolo baahida loo qabo paclitaxel ee suuqa dawooyinka, saynisyahannadu waxay sameeyeen cilmi-baaris ballaaran, hababka semi-synthetic waxay noqdeen hab muhiim ah oo wax soo saar ah.Maqaalkani wuxuu soo bandhigi doonaa habka semi-synthesizing paclitaxel ee 10-deacetylbaccatin III (10-DAB) wuxuuna xooga saarayaa muhiimada uu leeyahay goobta daroogada.

Paclitaxel, oo asal ahaan ka go'doonsan jilif geedka yew ee Pacific-ga, ayaa caan ku ah astaamaheeda heersare ah ee ka hortagga kansarka.Si kastaba ha ahaatee, yew Baasifiga waa kheyraad dabiici ah oo dhameystiran, kuma filna in la daboolo baahida caafimaad ee casriga ah ee paclitaxel.Horumarinta hababka semi-synthetic waxay ka dhigtay wax soo saarka ballaaran ee paclitaxel mid macquul ah, iyadoo 10-deacetylbaccatin III ay tahay dhexdhexaad muhiim ah.

Diyaarinta 10-DAB ee Semi-Synthetic Paclitaxel:

10-DAB waa dhex dhexaad muhiim u ah dariiqa semi-synthetic ee loo maro paclitaxel wuxuuna u baahan yahay dhowr tillaabo diyaarintiisa.Caadi ahaan, isku dhafka 10-DAB wuxuu ku bilaabmaa horudhaca dabiiciga ah ee paclitaxel, taxuyunnanine C, oo ka soo jeeda baccatin III.Baccatin III marka hore waa deacetylated si uu u soo saaro 10-deacetylbaccatin III.Intaa ka dib, 10-deacetylbaccatin III waxay martaa falcelino kala duwan, oo ay ku jiraan hydrogenation, beddelaad, epoxidation, hydrolysis, iyo in ka badan, ugu dambeyntii isu beddela 10-DAB.

Codsiyada 10-DAB ee Semi-Synthetic Paclitaxel:

Isku-dubaridka 10-DAB ayaa furay waddo cusub oo loogu talagalay semi-synthesis of paclitaxel, taasoo bixisa joogtaynta wax soo saarka daroogada.Paclitaxel waa daawo kansar ka hortag oo ballaaran oo loo isticmaalo daawaynta noocyada kala duwan ee kansarka, oo ay ku jiraan ugxan-sidaha, naaska, iyo kansarka sanbabada.Jidka semi-synthetic-ga wuxuu yareeyaa kharashka wax soo saarka daroogada, taasoo ka dhigaysa doorashadan daaweynta muhiimka ah mid aad u heli kara bukaanada.

Gabagabo:

Habka semi-synthesizing paclitaxel ee 10-DAB wuxuu ku guuleystey guulo la taaban karo oo ku saabsan isku-darka daroogada.Ma aha oo kaliya in ay wax ka qabato arrinta ilaha dabiiciga ah ee xaddidan ee paclitaxel laakiin sidoo kale waxay kor u qaadaysaa waxtarka wax soo saarka iyo joogtaynta.Farsamadani waxay ka dhigan tahay horumar laga gaaray soo saarista dawooyinka ka hortagga kansarka waxayna ballan qaadaysaa horumar dheeraad ah oo dhanka caafimaadka ah si loola dagaallamo cudurrada halista ah sida kansarka.Mustaqbalka, cilmi-baarayaashu waxay sii wadi doonaan inay hagaajiyaan hababka isku-dhafka ah si loo hagaajiyo waxtarka oo loo yareeyo kharashyada, ugu dambeyntii faa'iido u leh bukaanno ballaaran.

Fiiro gaar ah: Faa'iidooyinka iyo codsiyada suurtagalka ah ee lagu xusay maqaalkan waxay ku salaysan yihiin suugaanta dadweynaha ee la heli karo.

Akhrin dheeraad ah: Yunnan Hande Biotech Co., Ltd., oo leh 26 sano oo diiradda lagu saaray wax soo saarka paclitaxel, waa soo saaraha madax-bannaan ee caalamiga ah ee la ansixiyay ee dhirta laga soo saaro daawada kansarka ka hortagga ah ee paclitaxel maaddooyinka dawooyinka firfircoon, oo ay aqoonsan yihiin wakaaladaha sharciyeynta sida US FDA, European EDQM , Australia TGA, China CFDA, India, Japan, iyo kuwa kale.Yunnan Hande Paclitaxel, oo laga heli karo kaydka, waxaa si toos ah u iibisa soo saaraha.Fadlan si xor ah u wac wixii su'aalo ah +86 18187887160 (WhatsApp).