Paclitaxel waa mid ka mid ah dawooyinka kemotherabi ee saddexda jiil ee caadiga ah, laakiin milmaheeda biyuhu aad bay u liitaan waxayna u baahan yihiin in lagu milo dareerayaasha organic. kaliya waxay ka fogaataa dareen-celinta sunta ah ee ay keenaan dareerayaasha organic, laakiin sidoo kale uma baahna pretreatment hormon; Waxay kaloo ka dhigi kartaa albumin inay si degdeg ah u qaadaan paclitaxel ee wareegga dhiigga, waxay sii maraan unugyada endothelial iyada oo loo marayo receptor dhexdhexaadiye endocytosis, oo kobciya unugyada burooyinka iyada oo loo marayo saamaynta sare ee xajinta iyo xajinta (saamaynta EPR) ee burooyinka, taas oo sii wadata inay muujiso faa'iidooyinka farmashiyaha.
Xilligii immunotherapy, waxtarka hal daawo kuma filna, iyo heerka dhaafitaanka ujeeddada (ORR) ee daawadu kama badna 20%; Sida loo ballaariyo ka-faa'iidaystayaasha immunotherapy, daaweynta isku dhafan ayaa laga yaabaa in ay xal wax ku ool ah, kuwaas oo ka mid ah. Habka isku darka kemotherabi waa meesha kulul ee sahaminta hadda.
Marka laga eego dhinacan, albumin-ku-xidhan paclitaxel waxay leedahay faa'iidooyin u gaar ah, ORR-keedu wuu sarreeyaa, wuxuu u dili karaa unugyada burooyinka si wax ku ool ah, wuxuuna kor u qaadaa soo-gaadhista antigen-ka burada; unugyo caadi ah.
Fiiro gaar ah: Waxtarka suurtagalka ah iyo codsiyada lagu soo bandhigay maqaalkan dhamaantood waxay ka yimaadeen suugaanta la daabacay.
Yunnan Hande Biotechnology Co., Ltd ayaa ku takhasusay wax soo saarkapaclitaxel APIin ka badan 20 sano, oo waa mid ka mid ah saarayaasha madax-bannaan ee adduunka ee paclitaxel API, a warshad-ka soo jeeda daawada kansarka, ansixiyay US FDA, Yurub EDQM, Australian TGA, Chinese CFDA, India, Japan iyo hay'adaha kale ee sharci qaran. .Hande ma bixin karo oo keliya tayada sarealaabta ceeriin paclitaxel,laakin sidoo kale adeegyada cusboonaysiinta farsamada ee la xidhiidha qaabaynta paclitaxel. Wixii macluumaad dheeraad ah, fadlan xor u noqo inaad nagala soo xidhiidho 18187887160.
Waqtiga boostada: Dec-29-2022