Paclitaxel waa walax laga soo saaro yew, taas oo si wax ku ool ah u joojin karta kansarka waana daawada si weyn loo isticmaalo xiddiga ka hortagga kansarka ee adduunka. 1960-meeyadii, farmashiyeyaal Maraykan ah ayaa go'doomiyay taxol laga soo qaatay jilif Pacific yew, warshad Taxus ah. Kadib in ka badan 20 sano Cilmi-baaris caafimaad, cirbadeynta paclitaxel-ka ee ugu horreysay "Taxol" ayaa la bilaabay 1992. Ilaa hadda,paclitaxelWaxay leedahay sifooyinka waxtarka sare leh, sunta hoose iyo spectrum ballaaran. Waxay leedahay saameyn daweyn cad oo ku saabsan kansarka ugxan-sidaha, kansarka naasaha, Melanoma malignant, kansarka sanbabada, kansarka qanjirka 'prostate', maskaxda. kansarka iyo kansarka mindhicirka.
Natiijooyinka tijaabooyinka caafimaadku waxay muujinayaan, hadda, helitaankapaclitaxel APIsInta badan waxay ku xiran tahay soo saarista dhirta Taxus chinensis iyo kiimikaad Semisynthesis. Cilmi-baarayaasha sayniska waxay soo ururiyaan laamo macmal ah iyo caleemaha Taxus chinensis chinensis, isticmaal soo saarista dareeraha, saarista wajiga adag, saarista dareeraha supercritical, kala soocida xuubabka, kala saarida chromatographic iyo hababka kale ee kala saarista iyo soo saarista soo saar horudhacyo la mid ah qaab-dhismeedka paclitaxel, sida bacatine III,10 deacetyl bacatine III, iwm.,kadibna hel dawooyinka bulk paclitaxel daawo iyadoo wax laga beddelayo kiimikaad ee hababka wax soo saarka tirada badan.
Sida laga soo xigtay xisaabaadka saynisyahano, bukaanada kansarku waxay u baahan yihiin inay isticmaalaan wax ka badan 2 garaam oo ahpaclitaxelIn hal kooras oo daawaynta ah. Raadkan paclitaxel waxay u baahan yihiin in laga soo saaro jilif 4-8 geedo Taxus chinensis duurjoogta ah oo koray in ka badan 50 sano. Dhanka kale, Taxus chinensis iyo paclitaxel ayaa ku yar, iyo Dhanka kale, waxaa jira baahi caafimaad oo aad u weyn, taas oo horseedaysa qiimaha sare ee alaabta ceeriin ee Taxus chinensis sanadka oo dhan, iyo sahayda ayaa hoos u dhacda baahida.
Sharaxaad:Wax ku oolnimada suurtagalka ah iyo codsiyada lagu sheegay maqaalkan waxay dhammaantood ka soo jeedaan suugaanta si guud loo heli karo.
Akhrinta dheeradka ah: Yunnan Hande Bio-tech waxa ay inta badan ku hawlan tahay soo saarista iyo horumarinta cashuuraha.Waxyaabaha ugu muhiimsan waa Paclitaxel,10-DAB Semisynthesis Paclitaxel,10-DABIII,docetaxel,cabataxel,iwm.Haddii aad u baahan tahay inaad wax ka ogaato paclitaxel ku salaysan. alaabta ceeriin, fadlan xor u noqo inaad nala soo xiriirto.
Waqtiga boostada: Juun-14-2023